Research

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  • Two Kinds of A Priori Infallibility
    Two Kinds of A Priori Infallibility
    On rationalist infallibilism, a wide range of both (i) analytic and (ii) synthetic a priori propositions can be infallibly justified (or absolutely warranted), i.e., justified to a degree that entails their truth and precludes their falsity. Though rationalist infallibilism is indisputably running its course, adherence to at least one of the two species of infallible a priori justification refuses to disappear from mainstream epistemology. Among others, Putnam (1978) still professes the a priori infallibility of some category (i) propositions, while Burge (1986, 1988, 1996) and Lewis (1996) have recently affirmed the a priori infallibility of some category (ii) propositions. In this paper, I take aim at rationalist infallibilism by calling into question the a priori infallibility of both analytic and synthetic propositions. The upshot will be twofold: first, rationalist infallibilism unsurprisingly emerges as a defective epistemological doctrine, and second, more importantly, the case for the a priori infallibility of one or both categories of propositions turns out to lack cogency., This paper is forthcoming in Synthese.
    Two-Dimensional Velocity Estimation for Doppler Optical Coherence Tomography
    Two-Dimensional Velocity Estimation for Doppler Optical Coherence Tomography
    Online version of a conference paper originally published as: Two-Dimensional Velocity Estimation for Doppler Optical Coherence Tomography, Darren Morofke, Michael C. Kolios, Victor X.D. Yang, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI, edited by James G. Fujimoto, Joseph A. Izatt, Valery V. Tuchin Proc. of SPIE Vol. 6429, 64292F, (2007) Publisher URL: http://spie.org/x648.html?product_id=701372
    UAV Based Relay for Wireless Sensor Networks in 5G Systems
    UAV Based Relay for Wireless Sensor Networks in 5G Systems
    Relay is one of the most significant issues in smart industrial wireless sensor networks (WSN) due to the low transmitting power of sensors. By relay, the signals of sensors can be concentrated at the relay and further transmitted to the base station for decreasing energy consumption in the system. In the past decades, the relay in WSN is generally one super sensor with large transmitting power. However, the placement of the super sensor is static, which leads to the instability of performance in WSN under the time-varying wireless environment. Fortunately, unmanned aerial vehicles (UAV) can provide an effective leverage to improve the environment-adaptation in WSN compared to the static relay in WSN. In this paper, we employ UAV as the relay in WSN, which can move in three-dimensional space to possess a better position to minimize the system power consumption. We use a simple case study to demonstrate the effectiveness of UAV in WSN. Extended simulations are also given to verify the preferable performance of the UAV based relay in WSN., Fu, S., Zhao, L., Su, Z., & Jian, X. (2018). UAV based relay for wireless sensor networks in 5G systems. Sensors (Basel, Switzerland), 18(8), 2413., (This article belongs to the Special Issue Smart Industrial Wireless Sensor Networks)
    Ultrasound Backscatter Signal Characterization and Classification Using Autoregressive Modeling and Machine Learning Algorithms
    Ultrasound Backscatter Signal Characterization and Classification Using Autoregressive Modeling and Machine Learning Algorithms
    Online version of a conference paper originally published as: Ultrasound Backscatter Signal Characterization and Classification Using Autoregressive Modeling and Machine Learning Algorithms N.R. Farnoud, S. Krishnan and M.C. Kolios In Proceedings of the 25th Annual International Conference of the IEEE EMBS (2003), pp. 2861-2864 Publisher URL: http://ieeexplore.ieee.org/xpls/abs_all.jsp?isnumber=28615&arnumber=1280515&count=256&index=223
    Ultrasound Microbubble Treatment Enhances Clathrin-Mediated Endocytosis and Fluid-Phase Uptake through Distinct Mechanisms
    Ultrasound Microbubble Treatment Enhances Clathrin-Mediated Endocytosis and Fluid-Phase Uptake through Distinct Mechanisms
    Drug delivery to tumors is limited by several factors, including drug permeability of the target cell plasma membrane. Ultrasound in combination with microbubbles (USMB) is a promising strategy to overcome these limitations. USMB treatment elicits enhanced cellular uptake of materials such as drugs, in part as a result of sheer stress and formation of transient membrane pores. Pores formed upon USMB treatment are rapidly resealed, suggesting that other processes such as enhanced endocytosis may contribute to the enhanced material uptake by cells upon USMB treatment. How USMB regulates endocytic processes remains incompletely understood. Cells constitutively utilize several distinct mechanisms of endocytosis, including clathrin-mediated endocytosis (CME) for the internalization of receptor-bound macromolecules such as Transferrin Receptor (TfR), and distinct mechanism(s) that mediate the majority of fluid-phase endocytosis. Tracking the abundance of TfR on the cell surface and the internalization of its ligand transferrin revealed that USMB acutely enhances the rate of CME. Total internal reflection fluorescence microscopy experiments revealed that USMB treatment altered the assembly of clathrin-coated pits, the basic structural units of CME. In addition, the rate of fluid-phase endocytosis was enhanced, but with delayed onset upon USMB treatment relative to the enhancement of CME, suggesting that the two processes are distinctly regulated by USMB. Indeed, vacuolin-1 or desipramine treatment prevented the enhancement of CME but not of fluid phase endocytosis upon USMB, suggesting that lysosome exocytosis and acid sphingomyelinase, respectively, are required for the regulation of CME but not fluid phase endocytosis upon USMB treatment. These results indicate that USMB enhances both CME and fluid phase endocytosis through distinct signaling mechanisms, and suggest that strategies for potentiating the enhancement of endocytosis upon USMB treatment may improve targeted drug delivery., Fekri F, Delos Santos RC, Karshafian R, Antonescu CN (2016) Ultrasound Microbubble Treatment Enhances Clathrin-Mediated Endocytosis and Fluid-Phase Uptake through Distinct Mechanisms. PLoS ONE 11(6): e0156754. doi:10.1371/journal.pone.0156754
    Understanding Internet Usage Among Broadband Households: A Study of Household Internet Use Survey Data
    Understanding Internet Usage Among Broadband Households: A Study of Household Internet Use Survey Data
    Statistics Canada, Science, Innovation and Electronic Information Division Working Papers, Catalogue no. 88F0006X, no. 3, ISSN 1706-8967, ISBN 978-0-662-48548-3, Statistics Canada, Science, Innovation and Electronic Information Division Working Papers, Catalogue no. 88F0006X, no. 3, ISSN 1706-8967, ISBN 978-0-662-48548-3
    Undressing Fashion Metadata: Ryerson University Fashion Research Collection
    Undressing Fashion Metadata: Ryerson University Fashion Research Collection
    The purpose of this poster is to provide insight into the processes involved in making a unique fashion research and teaching collection discoverable in an online environment at Ryerson University. The online collection will provide a means for the users to identify what artifacts are available for research purposes and facilitate teaching in the classroom. The poster will highlight effective metadata standards and elements, cross-domain metadata uses, metadata mapping and implementation., Eichenlaub, N., Morgan, M., & Masak-Mida, I. (2014, October). Undressing Fashion Metadata: Ryerson University Fashion Research Collection. Proceedings of the International Conference on Dublin Core and Metadata Applications, 195-197. Retrieved from http://dcpapers.dublincore.org/pubs/article/view/3723/1946, Papers, Project Reports and Posters for DC-2014 in Austin, Texas, 8-11 October 2014
    Unmediated is the Message: Enhancements to Traditional Interlibrary Loan in a Canadian University
    Unmediated is the Message: Enhancements to Traditional Interlibrary Loan in a Canadian University
    This paper discusses the implementation and delivery, at Ryerson University Library in Canada, of three consortially-facilitated, user-centered initiatives to enhance traditional interlibrary loan services. Through a collaborative purchase of approximately 4,000 NetLibrary ebooks, with the Ontario Council of University Libraries (OCUL) consortium and the Consortium of Ontario Libraries, the Library provides unmediated access to shared monographs. Ryerson's fully-subsidized document delivery service allows users to order journal articles directly from the Canada Institute for Scientific and Technical Information (CISTI Source) database., Originally published in: Interlending & Document Supply, 32(3): 152-158. Publisher URL: http://www.emeraldinsight.com/10.1108/02641610410551978
    Urban resilience in Canada : research priorities and best practices for climate resilience in cities.
    Urban resilience in Canada : research priorities and best practices for climate resilience in cities.
    Brown, C., Shaker, R.R., Gorgolewski, M., Papp, V., & Alkins, S. (2016). Urban resilience in Canada: Research priorities and best practices for climate resilience in cities. [Technical report]. 1-39. Available from: http://digital.library.ryerson.ca/islandora/object/RULA%3A4286
    Urgency is a non-monotonic function of pulse rate
    Urgency is a non-monotonic function of pulse rate
    Magnitude estimation was used to assess the experience of ur- gency in pulse-train stimuli (pulsed white noise) ranging from 3.13 to 200 Hz. At low pulse rates, pulses were easily resolved. At high pulse rates, pulses fused together leading to a tonal sensation with a clear pitch level. Urgency ratings followed a nonmonotonic (polynomial) function with local maxima at 17.68 and 200 Hz. The same stimuli were also used in response time and pitch scaling experiments. Response times were negatively corre- lated with urgency ratings. Pitch scaling results indicated that urgency of pulse trains is mediated by the perceptual constructs of speed and pitch.